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Exousia Bio

Our Science

Targeting What Conventional Therapies Miss

Four core innovations underpin the platform — from nucleic-acid delivery to blood-brain barrier transit and cancer stem cell targeting.

01

Targeting cancer stem cells

Targets NANOG to overcome tumor stemness and chemoresistance — the mechanisms most associated with recurrence after standard therapy.

02

Crossing the blood-brain barrier

Brain-homing peptide (BHP)-engineered exosomes are designed for targeted delivery to the brain.

03

Precision exosome delivery

Engineered exosomes enable targeted delivery of therapeutic nucleotides — shRNA, siRNA, and DNA — to difficult-to-treat tumors.

04

Regulatory milestones

FDA Orphan Drug Designation for malignant glioma, and a positive opinion from the EMA’s Committee for Orphan Medicinal Products.

Exosomes as delivery vehicles

Exosomes are naturally occurring extracellular vesicles that transfer biological material between cells. Exousia Bio engineers them as targeted delivery vehicles for selected therapeutic cargo, including nucleic-acid-based material.

 

The approach is being investigated in combination with established anticancer therapies, with the objective of improving delivery and effectiveness against malignant cells — including the cancer stem cells believed to play an important role in tumor recurrence.